Nigro protocol is the preoperative use of chemotherapy with 5-fluorouracil and mitomycin and medical radiation for squamous cell carcinomas of the anal canal. Success of the preoperative regimen changed the paradigm of anal cancer.
Epidermoid Cancers of the Anal Canal: Current Treatment. Jennifer Keywords: Anal canal malignancy, epidermoid carcinoma, chemoradiation, Nigro protocol.
Keywords: Anal cancer, Squamous cell cancer, Nigro protocol, Anal intraepithelial neoplasia, Chemoradiation therapy, Anal neoplasm.